Discover the Healing Powers of Carbon Dioxide
BodyStream is a revolutionary technology allowing you to experience the healing powers of carbon dioxide from the comfort of your own home.
When I saw myself in the mirror I nearly fainted! The bags under my eyes were GONE! And my legs, that seem to have crocodile skin, after the BodyStream CO2 Bath now feels soft and supple, almost like a baby’s bottom.
Victoria Heaps
47, Stockholm
Why Carbon Dioxide?
When we inhale we take in oxygen, which is used to produce energy (ATP) efficiently. In this process of manufacturing energy, which is called metabolism, our body also produces heat, water, and carbon dioxide. The excess carbon dioxide is exhaled. However, if we are stressed, our breathing will increase and we will exhale too much CO2. If we are inactive, our metabolism will decrease, and less CO2 is produced. Combining the two, stress and inactivity, has a double negative effect resulting in lower levels of carbon dioxide in our body.
Since carbon dioxide has many important properties in our body, we may experience health challenges when the CO2 levels go down. One effect of CO2 is that it creates vasodilation, which allows greater blood flow to the cells, which in turn means increased oxygen delivery and improved removal of waste products.
The heart will have to work less hard to pump the blood through your circulatory system, and this will activate the parasympathetic nervous system, which creates a state of relaxation throughout the entire body,
In the morning I cried like a baby with the worst period cramps I’ve had.
I was cramping pretty badly throughout the day. Later that evening I took my first BodyStream CO2 bath and after 5-10 minutes all my cramps went away.
Normally I also bleed pretty bad, but this time I had much less bleeding than normal. And instead of 7-8 days my period only lasted 5 days.
THIS IS THE BEST PERIOD I’VE EVER HAD!
Maria Atlee
28
WHAT IS THE BodyStream?
The BodyStream is a system designed to help bathe the entire body (up to the neck) in carbon dioxide gas. Once you’re in the BodyStream suit, at first all the air is vaccum pumped out and then the suit is filled up with 100% carbon dioxide. The CO2 is then absorbed through your skin, which will open up your blood vessels.
Many people report feeling very relaxed and will even fall asleep while using the BodyStream. A parasympathetic deluxe experience.
See BodyStream in Action
Carbon Dioxide Therapy for Cellulite
Carbon dioxide (CO2) therapy has been shown to be a very effective treatment for the reduction of cellulite. Normally it takes between 10 to 15 sessions to see significant improvement.
In a study published in August 2016 they found significant reductions in cellulite. The study below used injections of carbon dioxide but carbon dioxide bathes have shown that CO2 can be absorbed through the skin transdermally like in the BodyStream bath.
Photos from this study using carboxytherapy for cellulite.
A and C are before the carboxytherapy treatment and B and D are 7 days after the last treatment.
Results: After the treatment, there was a significant reduction (P=0.0025) of the cellulite from degree III to degree II, and this improvement had correlation with the improvement in the organization of the fibrous lines and the disposal of adipose tissue lines of the treated regions observed through the panoramic ultrasound images diagnosis.
Conclusion: Carboxytherapy is an effective technique of treatment of cellulite in the
buttocks region and posterior thighs of healthy women.
Carbon Dioxide Therapy in the Treatment of Cellulite: An Audit of Clinical Practice
Results –
A total of 101 women underwent abdominal therapy (Table 1). A significant reduction in upper, mid, and lower abdomen circumference occurred in all three age groups: respectively, 1.8 ± 0.5, 1.6 ± 0.4, and 2.1 ± 0.3 cm in the 20- to 29-year-old group, 1.6 ± 0.4, 2.3 ± 0.3, and 2.1 ± 0.3 cm in the 30- to 39-year-old group, and 2.0 ± 0.4, 2.5 ± 0.4, and 2.6 ± 0.4 cm in the 40- to 50-year-old group. For the 10 men who underwent the same therapy, the fall in abdominal circumference was not significant. For the 57 women who underwent thigh therapy (27 in the 20- to 29-year-old group, 18 in the 30- to 39-year-old group, and 12 in the 40- to 50-year-old group), thigh circumference was significantly reduced respectively in the right versus left thigh 1.6 ± 0.3 versus 1.5 ± 0.2 cm, 1.1 ± 0.3 versus 1.1 ± 0.3 cm, and 1.6 ± 0.3 versus 1.5 ± 0.4 cm.
Ultrasound examination of the abdomen showing measurement of subcutaneous fat befor and after carbon dioxide therapy. The subepidermal thickness is reduced.
Physiology Basics of Carbon Dioxide
1. The Bohr Effect allows more oxygen to get to the tissues. The Bohr Effect states that the oxygen loses its affinity for hemoglobin due to the presence of carbon dioxide allowing the nearby cells to utilize oxygen more efficiently. More oxygen utilization in turn also produces more carbon dioxide.
2. How CO2 is stored in the bones. Submarine studies show that over several months they would store up to 10 pounds of CO2 in the bones. Additionally there is something called Marble Bone Disease or Osteopetrosis. It is a condition where there is a deficiency of carbonic anhydrase causing CO2 in the body to build up to higher than normal levels.
3. The body can store 120 liters of CO2, but this is mostly as bicarbonate. 120 liters is only about .48 lbs.
4. CO2 being stored in the body in carbamino groups changing the function of amino and protein groups. Carbaminos also protect cells from glycation like in diabetes, as well as from oxidative damage.
https://www.sciencedirect.com/science/article/pii/S1044030510003430
At high pH and in the presence of dissolved CO2, the N-terminus and ε-amino groups of amino acids, peptides, and proteins can form adducts with CO2, known variously as carbamino groups, carbamino acids, carbamates, carbamides, or carbo amino groups [1] C. Stadie, H.J. O’Brien
The Equilibrium of Amino Acids, Carbon Dioxide, and Carbamates in Aqueous Solution: with a Note on the Ferguson-Roughton Carbamate Method J. Biol. Chem., 112 (1936), pp. 723-758
The formation of carbamino groups alters the electrostatic properties of peptides and proteins and can have many different effects. For example,
carbamino groups can change peptide conformation [1], influence peptide degradation and receptor binding [2], and increase the neurotoxicity of amino acids [3]. Carbamino groups increase the stability of insulin dimers [4] and are required for metal binding at the active sites of ribulose-1,5-biphosphate carboxylase oxygenase (RUBISCO) [5] and urease [6]. Carbamino group formation at the N-termini changes the oxygen binding properties of hemoglobin [8, 9, 10, 11, 12] and allows hemoglobin to transport carbon dioxide [13, 14, 15]. Nearly any peptide or protein that does not have the N-terminus blocked is subject to the formation of carbamino groups
5. It’s our number one anti-inflammatory.
The results testify to the fact that CO2 is a powerful inhibitor of reactive oxygen species (ROS) generation by cells (blood phagocytes and alveolar macrophages of 96 people and cells of inner organs and tissue phagocytes (of liver, brain, myocardium, lungs, kidneys, stomach, and skeleton muscles), as well as by mitochondria of the liver of 186 white mice and human tissues.
Effect of carbonic acid concentration in blood on content of keto-acids and redox state of nicotinamide coenzymes in rabbit tissues
A rise in the level of carbonic acid in animal blood at practically unchanged pH causes an increase in the value of free [NAD+]/[NADH] and [NADP+]/[NADPH] ratios in the liver cells cytoplasm. The increase in the oxidizing power of the liver cells cytoplasm is observed against a background of a rise in both the total level of keto-acids in blood and concentration of pyruvate oxaloacetate and alpha-ketoglutarate in the liver and kidneys of animals.
Evidence points to the ability of CO2 to favor the oxidized state of the cell, directly increasing the ratio of NAD+ to NADH.
NAD+ levels decline when you age. When you are 50 years old, you have half the levels of NAD+ as you do when you are 20.
7. CO2 acting as a Lewis Acid
An unhealthy cell or cancer cell is in an overly reduced state having an excess of electrons and being more alkaline. In the presence of carbon dioxide, it acts like a Lewis Acid, withdrawing electrons from excited protons and facilitating oxygen delivery and restoring a healthy oxidative metabolism
9. CO2 has an effect on removing water from the cell and contributing to the structured jellylike state of the cell. When CO2 is formed in the cell it forms carbonic acid which is the combination of water and carbon dioxide. As it is formed, it is streamed out of the cell. Too much water in the cell causes the water in the cell to be less structured.
Carbon Dioxide Therapy - A Neurophysiological Treatment of Nervous Disorders by
L.J. Meduna M.D published in 1950.
Carbon dioxide has a direct effect on increasing your resiliency to handling stress and producing energy. Meduna in 1950 observed the following changes to nerve cells in the presence of higher co2.
1. Increase in the member potential.
2. Increase in the threshold of stimulation.
3. Increase in ability to release energy.
4. Decrease in fatigability
A more general description of the effect of CO2 upon the functional ability of the nerve is given by Lorente de No:
1. The ability of the nerve fibers to release energy which is required to maintain the flow of the demarcation current or what amounts to the same thing to withstand without failure the effect of an applied cathodal current is increased markedly by the presence of 5% CO2 in the atmosphere of the nerve.
2. CO2 increases the ability of the nerve to conduct trains of impulses because the presence of 5% CO2 in the atmosphere of the nerve noticeably delays the appearance of the signs of failure, namely, increase of threshold, decrease of speed of conduction, decrease of the height of the spike.
Thus, it can be said that the presence of 5% CO2 increases the ability of the nerve to perform work, undoubtedly because the enzymatic mechanisms of the nerve utilize stores of metabolic energy more readily or more effectively in the presence than in the absence of a certain concentration.
The presence of CO2 in the atmosphere of the nerve not only increases the value of the membrane potential of the resting nerve, but also prevents the progressive depolarization of the nerve during tetanic stimulation.
What in the world is it that you have created???! This is probably the coolest thing I’ve ever tried. I felt high, invincible and immune to negative thoughts for 12 hours after the BodyStream therapy! I don’t think I’ve ever been this happy.
My knee felt fantastic and I could run for the first time in a year. I was so happy that I was about to cry. It has been so bad that for about four months now I haven’t even been able to go for a short walk. Every step has been painful.
Alexandra Kolam
personal trainer, massage therapist
FOR WHAT CAN THE BodyStream BE USED?
The BodyStream improves overall cellular health on all levels so it may be used to improve health and outcome in a wide variety of health conditions. It may be used for skin wound healing or it may be the soft tissue, or even the joint.
Carbon dioxide baths have been known to reduce body pain, increase metabolic rate and fat burning, increase in energy and for firming, softer and more youthful looking skin. Even if you have no health issues currently you can use it to take your health to the next level, have more energy, recover from fatigue faster and increase your overall vitality.
Exposing the body to carbon dioxide, increases oxygen delivery to
muscles, organs, brain, and more; it dilates arteries to increase blood flow, helps dissolve more fat, and is a powerful treatment for dozens of
ailments.
I have tried the BodyStream carbon dioxide bath more than 20 times and I really like the effect! I get more energy and an inner peace that allows me to concentrate better. When I train, I get a lower heart rate, less lactic acid, faster recovery and better performance.
All of this is invaluable in my profession as a Rally Driver. Everyone should try the carbon dioxide bath and discover the benefits!
Emil Lindholm
Rally Driver
BENEFITS OF USING THE BodyStream
Carbon dioxide baths help all of your cells use oxygen more efficiently, giving you energy and youthfulness.
Increase in energy
Anti-Aging
Reduced Stress and Anxiety
Reduction in cellulite
Firmer and more youthful skin on the entire body
Faster healing of wounds
Increased metabolic rate and fat burning
Reduction in body pain
Increased microcirculation
Improved skin quality
Reduction of cellulites, spider veins and varicose veins
The CO2 suit has proven to be very beneficial in terms of a feeling of relaxation and calmness. I used it initially with my motocross rider 3 times and he was able to participate in his championship a week earlier than expected without any adverse reactions, which was incredible considering he was only 3 weeks post injury (fractured ribs, scapula and wrist). I have used it more recently with stressed patients and they have reported a great feeling of calmness. Currently i am using it with a client suffering from fibrosis of the lung – alongside breathing techniques – to try and increase his aerobic capacity.
Alex Dalton
Axholme Physiotherapy
WHEN DO I USE THE BodyStream?
FOR DIFFERENT HEALTH ISSUES
- Pain
- Inflammation and swelling
- Muscle Soreness
- Lymphatic problems
- Low Energy
- Poor circulation
- Sleeping problems
- Weight loss and toning
IN STRESS AND DIFFICULT EMOTIONS
- Stress, Worry, Anxiety, Addiction
- Cravings
BEFORE OR AFTER PHYSICAL ACTIVITY
- As a performance enhancer
- As a recovery tool
Helena Hvistendahl Philipson
HOW DO I USE THE BodyStream?
Our BodyStream carbon dioxide dry bath allows you to easily bathe in an environment of 100% CO2.
The BodyStream carbon dioxide bath is very easy to use. You first vacuum out all the air and then fill the suit with 100% carbon dioxide to the desired fullness and pressure. It’s built with a neck seal and an airtight zipper to allow you to easily get into the suit, while retaining all of the CO2, ensuring that it’s at 100%.
The BodyStream carbon dioxide bath is a convenient way to cover your entire body with CO2 from your feet all the way to your neck, including your arms and hands. The CO2 dry bath allows carbon dioxide to be delivered into the body through the skin (carbon dioxide is easily absorbed through the skin).
CO2 Effect on Physiology - Scientific Studies
- The inefficient healing of chronic wounds is a result of poor blood perfusion at the wound and surrounding tissues.
- During CO2 therapy the LD flux in the studied extremity increased from 5.8 PU ± 3.9 PU to 30.3 PU ± 16.7 PU
- CONCLUSIONS: Our results confirm a local vasodilatory effect of applied CO2 therapy.
- Diabetic foot. It is the most common foot injury in diabetic patients and can lead to lower-extremity amputation.
- Carboxytherapy refers to the subcutaneous injection of CO2 to improve the microcirculation and promote wound-healing by stimulating the microcirculation
- The results showed that this treatment that included carboxytherapy promoted wound-healing and prevented amputation.
- In their study, 42 patients were divided into three groups: A, B, and C.
- In Group A, only liposuction was performed.
- In group B 3 weeks after liposuction CO2 therapy was administered in two weekly subcutaneous applications of CO2 for 10 consecutive weeks.
- In group C, CO2 therapy alone was administered with the same contingencies used for group B (two weekly subcutaneous applications of CO2 for 10 consecutive weeks).
- This study has shown that with CO2 therapy to obtain improvement in skin irregularity and cutaneous elasticity is possible.
- Our study has shown the positive response to reduced fat accumulation.
- This was confirmed by analysis of the results obtained by measurement of thigh circumference in group B than in group A.
- Particularly interesting were the effects on skin elasticity
“It seems essential to use procedures stimulating the production of collagen, such as radiofrequency, intense light source, LED light (light-emitting diode), IR (infrared light), laser treatments, and chemical peels in activities aiming to improving skin elasticity. Nevertheless, none of these treatments has long-lasting effects related to the improvement of skin microcirculation which seems to be a factor necessary for proper functioning of various cells, including fibroblasts. It has been demonstrated that carboxytherapy improves cutaneous circulation, which is mirrored by overall improvement of skin function. Brandi et al. performed a study, in which local application of carbon dioxide was associated with a mean increase in skin elasticity by 55%. In other study by Brandi et al., subcutaneous and intradermal administration of carbon dioxide resulted in the increase in the production of new collagen and the degradation of old one. The arrangement of new collagen was characteristic for the skin of young organisms. Studies have also demonstrated the appearance of new capillary vessels (Brandi et al., 2001, 2004, 2012).”
“Carboxytherapy seems to be the only method that affects all signs of skin aging, including the loss of skin elasticity, wrinkles, shadows, swelling, and fat hernia under the eyes.”
Mitochondrial dysfunction is a hallmark of metabolic decline during aging. Chini and colleagues found that cells consume less oxygen, have increased lactate levels, and possess irregular mitochondria (Camacho-Pereira et al., 2016). (CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism. Camacho-Pereira J, Tarragó MG, Chini CCS, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN Cell Metab. 2016 Jun 14; 23(6):1127-1139.
- (1) the gene expression of PGC-1α, silent mating type information regulation 2 homologs 1 (SIRT1) and VEGF, and increased the number of mitochondria, as proven by real-time PCR and immunohistochemistry,
- (2) muscle fiber switching in the TA muscle, as proven by isolation of myosin heavy chain and ATPase staining
- Peroxisome proliferators-activated receptor (PPAR)-gamma coactivator-1 (PGC-1α) is up-regulated as a result of exercise and mediates known responses to exercise, such as mitochondrial biogenesis and muscle fiber-type switching, and neovascularization via up-regulation of vascular endothelial growth factor (VEGF).
- PGC-1α is up-regulated as a result of exercise such as mitochondrial biogenesis and muscle fiber-type switching, and up-regulation of VEGF.
- We demonstrated transcutaneous application of CO2 up-regulated the gene expression of PGC-1α, SIRT1 and VEGF, and instance of muscle fiber switching.
- Transcutaneous application of CO2 may cause similar effect to aerobic exercise in skeletal muscle.
- Laser Doppler perfusion imaging demonstrated that the blood flow in the fractured limb was significantly greater at weeks 2 and 3 in the CO2/hydrogel group
- (p < 0.05; 95% CI for the difference, 8.4% to 22.4% and 6.7% to 19.0%, respectively).
- Gene expression of chondrogenic, osteogenic, and angiogenic markers was significantly greater in the CO2/hydrogel group at several time points.
- Ultimate stress, extrinsic stiffness, and failure energy (relative to the contralateral limb) were significantly greater in the CO2/hydrogel group at week 3
- (p < 0.05; 95% CI for the difference, 24.8% to 67.5%, 4.0 % to 22.7%, and 9.6% to 58.8%, respectively).
Topical cutaneous application of CO2 by means of a hydrogel accelerated fracture repair in association with the promotion of angiogenesis, blood flow, and endochondral ossification.
- Radiographically, bone healing rate was significantly higher in the CO2 group than in the control group at 4 weeks (18.2% vs. 72.7%).
- The ultimate stress, extrinsic stiffness, and failure energy were significantly greater in the CO2 group than in the control group at 4 weeks
- Gene expression of vascular endothelial growth factor in the CO2 group was significantly greater than that in the control group at 3 weeks
- CONCLUSIONS: Topical cutaneous application of CO2 accelerated bone healing in a rat femoral defect model. CO2 application can be a novel and useful therapy for accelerating bone healing in bone defects.
- The fracture union rate was significantly higher in the 3w-CO2 group than in the control group (p < 0.05). Histological assessment revealed promotion of endochondral ossification in the 3w-CO2 group than in the control group. In the biomechanical assessment, all evaluation items related to bone strength were significantly higher in the 3w-CO2 group than in the control group
- CONCLUSIONS: The present study, conducted using an animal model, demonstrated that continuous carbon dioxide application throughout the process of fracture repair was effective in enhancing fracture healing.
- RESULTS: Nineteen patients were subjected to complete analysis. No adverse events were observed. Arterial and expired gas analyses revealed no adverse systemic effects including hypercapnia. The mean ratio of blood flow 20 min after CO2 therapy compared with the pre-treatment level increased by approximately 2-fold in a time-dependent manner.
- CONCLUSIONS: The findings of the present study revealed that CO2 therapy is safe to apply to human patients and that it can enhance blood flow in the fractured limbs.
- Muscle weight was significantly higher in the CO2 group than in the control group.
- Histological analysis revealed that the muscle fiber cross-sectional area was reduced in both groups. Nevertheless, the extent of atrophy was lesser in the CO2 group.
- Muscle fibers in the control group tended to change into fast muscle fibers. Vascular staining revealed that more capillary vessels surrounded the muscle fibers in the CO2 group
- CO2 group had a significantly enhanced expression of genes that were related to muscle synthesis.
- Transcutaneous CO2 application may be a novel therapeutic strategy for preventing skeletal muscle atrophy after fracture.
- The acceleration of nerve regeneration remains a clinical challenge.
- Scores for the sciatic function index and pinprick test were significantly higher in the CO2 group than control group.
- The muscle wet weight ratios of the tibialis anterior and soleus muscles were higher in the CO2 group than control group.
- Electrophysiological examination showed that the CO2 group had higher compound motor action potential amplitudes and shorter distal motor latency than the control group.
- Histological examination of the soleus muscle sections at postoperative week 2 showed shorter fiber diameter in the control group than in the CO2 group
- The mRNA expression of Atrogin-1 and MuRF-1 was lower, mRNA expression of VEGF and myogenin and MyoD was higher in CO2 group at postoperative week 2 compared to the control group.
- CLINICAL SIGNIFICANCE: Transcutaneous CO2 application has the therapeutic potential to accelerate the recovery of muscle atrophy in peripheral nerve injury.
- Injured muscle fibres were completely repaired at week six in the CO2-treated group but only partially repaired in the untreated group.
- expression levels of genes and proteins related to muscle protein synthesis were significantly higher in the CO2-treated group
- significantly more capillaries four weeks after injury.
- CONCLUSION: Transcutaneous CO2 application can accelerate recovery after muscle injury in rats.
- CO2 therapy improved limited-extension ROM in the prevention group at 2 weeks (22° ± 2°) and 4 weeks (29° ± 1°) and in the treatment group at 2 weeks
- Muscular factors decreased in treated rats in the prevention group at 2 weeks (8° ± 2°) and 4 weeks (14°± 1°) and in the treatment group at 2 weeks (14 ± 1°) compared with untreated rats (15° ± 1°, 4.85-9.42; 16° ± 1°, 1.24-3.86; and 17° ± 2°, 1.16-5.34, respectively; all p < 0.05).
- The therapy improved articular factors in the prevention group at 2 weeks (4° ± 1°) and 4 weeks (6° ± 1°) and in the treatment group at 2 weeks (8° ± 1°) compared with untreated rats (10° ± 1°, 4.05-7.05; 12° ± 1°, 5.18-8.02; and 11° ± 2°, 1.73-5.50, respectively; all p < 0.05).
- CO2 therapy decreased muscle fibrosis in the prevention group at 2 weeks (p < 0.001). The expression of collagen Type 1, α1 mRNA in the biceps femoris decreased in treated rats in the prevention group at 2 and 4 weeks compared with untreated rat (p = 0.002 and p = 0.008, respectively)
- CO2 therapy decreased transforming growth factor beta immunolabeling in joint capsules in the rats in the prevention group at 2 weeks.
- CONCLUSION: CO2 therapy may be useful for preventing and treating contractures after spinal cord injuries. CO2 therapy particularly appears to be more effective as a prevention and treatment strategy in early-stage contractures before irreversible degeneration occurs, as shown in a rat model.
- We reported that carbon dioxide (CO2) water bathing accelerates skeletal muscle regeneration
- MyoD and myogenin play roles in muscle regeneration
- Tap water and CO2 (1,000 ppm) water bathing were performed at 37 °C for 30 minutes once a day.
- MyoD and myogenin were increased in the IC, ITW, and ICO2 groups compared with the NI group
- CONCLUSION: CO2 water bathing after muscle injury appears to induce an increase in the expression of myogenin.
- Exogenous CO2 by transcutaneous delivery promotes muscle fibre-type switching to increase endurance power in skeletal muscles.
- Running performance improved over the treatment period in the CO2 group, with a concomitant switch in muscle fibres to slow-type.
- The mitochondrial DNA content and capillary density in the CO2 group increased.
- CO2 was beneficial for performance and muscle development during endurance exercise
- Transcutaneous CO2 may enhance recovery from fatigue and support anabolic metabolism in skeletal muscles.
- Hyperglycemia impairs oxidative capacity in skeletal muscle.
- Transcutaneous carbon dioxide (CO2) enhances PGC-1α expression in skeletal muscle.
- These results indicate that transcutaneous CO2 improves impaired muscle oxidative capacity via enhancement of eNOS and PGC-1α-related signaling in the skeletal muscle of rats with hyperglycemia.
- Previous studies have demonstrated that decreased mitochondrial biogenesis is associated with cancer progression.
- In mitochondrial biogenesis, peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) regulates the activities of multiple nuclear receptors and transcription factors involved in mitochondrial proliferation.
- Previously, we showed that overexpression of PGC-1α leads to mitochondrial proliferation and induces apoptosis in human malignant fibrous histiocytoma (MFH) cells in vitro
- We also demonstrated that transcutaneous application of carbon dioxide (CO(2)) to rat skeletal muscle induces PGC-1α expression and causes an increase in mitochondrial proliferation.
- We show that transcutaneous application of CO(2) induces PGC-1α expression, and increases mitochondrial proliferation and apoptosis of tumor cells, significantly reducing tumor volume.
- Proteins involved in the mitochondrial apoptotic cascade, including caspase 3 and caspase 9, were elevated in CO(2) treated tumors
- We also observed an enrichment of cytochrome c in the cytoplasmic fraction and Bax protein in the mitochondrial fraction of CO(2) treated tumors, highlighting the involvement of mitochondria in apoptosis.
- Hypoxia plays a significant role in cancer progression, including metastatic bone tumors.
- We previously reported that transcutaneous carbon dioxide (CO2) application could decrease tumor progression through the improvement of intratumor hypoxia.
- In vivo results by μCT revealed that bone destruction was suppressed by transcutaneous CO2
- the expression of osteoclast-differentiation and osteolytic factors, as well as HIF-1α, was decreased in CO2-treated tumor tissues.
- multinucleated TRAP-positive osteoclasts were significantly decreased in CO2-treated tumor tissues.
- Hypoxic conditions promoted bone destruction in breast cancer metastasis, and reversal of hypoxia by transcutaneous CO2 application significantly inhibited metastatic bone destruction along with decreased osteoclast activity.
- The findings in this study strongly indicated that transcutaneous CO2 application could be a novel therapeutic strategy for treating metastatic bone destruction.
- Despite substantial improvements in surgery and chemotherapy, metastasis remains a major cause of fatal outcomes
- increases expressions of hypoxia inducible factor (HIF)-1α, matrix metalloproteinase (MMP)-2 and MMP-9, and can induce invasiveness
- As we previously showed a novel transcutaneous CO2 application to decrease HIF-1α expression and induce apoptosis in malignant fibrous histiocytoma, we hypothesize that transcutaneous CO2 application could suppress metastatic potential of osteosarcoma by improving hypoxic conditions.
- Transcutaneous CO2 application significantly decreased tumor growth and pulmonary metastasis in LM8 cells.
- Apoptotic activity increased, and intratumoral hypoxia was improved with decreased expressions of HIF-1α, MMP-2 and MMP-9
- In conclusion, we found that transcutaneous CO2 application can induce tumor cell apoptosis and might suppress pulmonary metastasis by improvement of hypoxic conditions with decreased expressions of HIF-1α and MMPs in highly metastatic osteosarcoma cell. These findings strongly indicate that this novel transcutaneous CO2 therapy could be a therapeutic breakthrough for osteosarcoma patients.
- present study, we investigated the relationship between the duration, frequency, and treatment interval of transcutaneous CO2 application and antitumor effects in murine xenograft models
- Murine xenograft models of three types of human tumors (breast cancer, osteosarcoma, and malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma)
- apoptosis was significantly induced by CO2 treatment for ≥10 min, and a significant decrease in tumor volume was observed with CO2 treatments of >5 min.
- The effect on tumor volume was not dependent on the frequency of CO2 application, i.e., twice or five times per week
- treatment using 3- and 4-day intervals was more effective at decreasing tumor volume than treatment using 2- and 5-day intervals
- optimal conditions of transcutaneous CO2 application to obtain the best antitumor effect in various tumors were as follows:
- greater than 10 min per application, twice per week, with 3- and 4-day intervals, and application to the site of the tumor.
- However, previous studies have not determined the sequential mechanism by which transcutaneous CO2 suppresses growth of epithelial tumors, including SCCs.
- In this study, we examined the effects of transcutaneous CO2 on cancer apoptosis and lymphogenous metastasis using human SCC xenografts.
- Our results showed that transcutaneous CO2 affects expressions of PGC-1α and TFAM and protein levels of cleavage products of caspase-3, caspase-9 and PARP, which relatives mitochondrial apoptosis.
- They also showed that transcutaneous CO2 significantly inhibits SCC tumor growth and affects expressions of HIF-1α, VEGF, MMP-2 and MMP-9, which play essential roles in tumor angiogenesis, invasion and metastasis.
– In conclusion, transcutaneous CO2
– suppressed tumor growth,
– increased mitochondrial apoptosis and – decreased the number of lymph node metastasis in human SCC by decreasing intra-tumoral hypoxia and suppressing metastatic potential
- Authors report their experience using carbon dioxide for the treatment of 48 patients presenting adipose accumulations, located on the thighs, knees, and/or abdomen.
- In conclusion, use of this transcutaneous CO2 gel produced changes in the dermis similar to those observed with subcutaneous injection of CO2.
- Hyrdogel enhances gas permeation through the skin.
By the age 30, oxygen levels in your skin drop by 25% and 50% by age 40. The body naturally gets its oxygen through breathing, but factors like stress, parasympathetic and sympathetic nervous system activity and availability of CO2. The body will first utilize oxygen in the major organs and lastly, go to the skin. When the skin doesn’t get enough oxygen it becomes more prone to aging, acne, redness, irritation and age spots.
Studies have shown achieving a significant aesthetic improvement within 2 to 6 months when the effects of collagen stimulation and remodeling become evident.
The results testify to the fact that CO2 is a powerful inhibitor of reactive oxygen species (ROS) generation by cells (blood phagocytes and alveolar macrophages of 96 people and cells of inner organs and tissue phagocytes (of liver, brain, myocardium, lungs, kidneys, stomach, and skeleton muscles), as well as by mitochondria of the liver of 186 white mice and human tissues.
Carbon dioxide (CO2) influence in generation of active oxygen forms (AOF) in human mononuclear cells (blood phagocytes and alveolar macrophages) and animal cells (tissue phagocytes, parenchymal and interstitial cells of liver, kidney, lung, brain and stomach)
It was established that CO2 in concentrations similar to those in blood (5.1%, pCO2 37.5 mmHg) and at high concentrations (8.2%, pCO2 60 mmHg; 20%, pCO2 146 mmHg) showed pronounced inhibitory effect on the AOF generation in all the studied cells (usually reducing it 2 to 4 times). Those results were obtained not only after the direct contact of isolated cells with CO2, but also after the whole body exposure to CO2.
Finally, it was established that CO2 led to the better coordination of oxidation and phosphorylation and increased the phosphorylation velocity in liver mitochondria. The results clearly confirmed the general property of CO2 to inhibit significantly the AOF generation in all the cell types
Very pleasant. I have had back pain for a long time due to an inflamed disc, after the first treatment the pain was completely gone. Unfortunately, the result did not last more than a couple of days. But clearly a strong physical and mental impact.
Viktor Khaled Frih
massage-therapist and yoga-instructor
What’s Included in Your BodyStream Order
Your BodyStream order includes
BodyStream suit
BodyStream therapy suit for
taking your CO2 baths
Suitcase
BodyStream Bag
To store and transport your
BodyStream Suit
Regulator
Inflation Gun
Connects to the BodyStream suit to inflate with CO2 gas from the regulator.
Vacuum
with CO2 to make sure your
bath is filled with only CO2
Regulator Wrench
Sleep Mask
To help you relax during the
BodyStream session blocking
light stimulus from entering
your eyes
ORDER NOW
Sizing Chart Considerations
If you are having multiple people use the BodyStream such as in your family or clinic/practice it’s best to use a large or purchase both medium and large. A small person can fit into the large suit, but it will just use up more CO2 in the session. It’s better to be too large than too small. However if you are the only person use the suit, go with the size closer to your body size as you will be able to be more mobile and it will use up less CO2. The differences in CO2 utilization between the two size suits are very significant.
Currently we have 3-4 weeks delivery time for all BodyStream orders!
We apologize for the inconvenience.
Please go ahead and place your order and we will do everything we can to deliver your order as soon as possible. Thank you for your patience and understanding!
FREQUENTLY ASKED QUESTIONS
Body Stream is often used by those who are healthy and want to be healthier, have more energy, increase vitality and maintain youthfulness.
Normally it is between 30 minutes to 1 hour for treatment, done 3 times per week. If you have an injury or would like to accelerate the benefits you can do it daily.
The BodyStream has not been approved to treat or cure any disease or illness by the FDA or any other organization.
The BodyStream is a tool to improve general wellness and is not to be used for any disease or illness. Please consult with a qualified doctor if you need medical help.